Sunday, May 6, 2012

Creatine, Part 2

May 6th, 2012

Yeah. That's a reference to Assassin's Creed II. Shame on you if you didn't realize that. You deserve to die and burn in hell.

Okay, so you finished Part 1. You learned what Creatine is and why you should take it. But now the question is, how do you take it? There's quite a few different Creatine products on the market today, but the one I want to cover the most is Creatine Monohydrate. Why? Because it is easily the most used and widely studied form available, and it has been around for quite a few decades as a supplement. Often times however, there is confusion as to how it is used. I will cover how I feel is the best way to supplement it, using science and anecdotal evidence for my reasoning why.

I will briefly talk about other Creatine products and their pros and cons, that way you can decide what is best for you.

So again, here is what I will cover today.

  • How to supplement Creatine
  • The different types of Creatine
  • The potential side effects of Creatine supplementation

How do you supplement Creatine?

Creatine Monohydrate is the trickiest form to take, but granted that it is taken correctly, it will yield the most results as far as energy production and muscle gain. Other forms are taken before your workout to assist ATP production which isn't bad, but as you remember from Part 1, Creatine taken after your workout will help increase muscle synthesis by lowering myostatin levels. So what is the optimal way to take Creatine Monohydrate? It should be understood that it can come in a pill form or a powder. I recommend the powder for what should be considered obvious reasons:

  1. It's A LOT cheaper
  2. It's surprisingly more convenient (swallowing 5 pills two to four times a day can be somewhat obnoxious)
  3. No gelatin capsule involved. Gelatin is basically ground up animal bones, usually that of a Pig. Pigs wallow in their own shit (which arguably is what I do on my days off from work.)

So yeah. The powder is better. Powders can also be "micronized", which means the particles are extremely FINE, and finer particles absorb better - it's that simple. I don't get too hung up about buying Micronized vs. Non-Micronized, I've tried both and can't say I've noticed a difference worth mentioning. I do know people who swear that micronized absorbs better, and that Creatine didn't work until they tried micronized. Having said that, and the fact that it would absorb better in theory, if you have the few extra bucks, go for it. If you don't, I think the regular stuff is fine.

Creapure® is trademarked form of Creatine Monohydrate hailing from Germany. (Leave it to the Germans...) It is manufactured to certain standards by a company who specializes in manufacturing Creatine, so there is a certain level of "trust" involved with buying Creapure. It could cost a little bit more money, so again, budget is a factor here. Personally, I wouldn't go crazy and insist on only taking Creapure, but there is something to be said for the quality assurance and manufacturing standards it must go through. This is up to you. If you feel better with it, go for it.

Alright so you bought a Creatine Monohydrate powder. How do we take it? Before anything, it's important to take note of what your fitness goals are at this point. Are you looking to build a ton of muscle mass? Do you just want some energy for the gym? Are you looking to get a "shredded look" for Summer? How you answer these questions will determine how you take Monohydrate. 

Creatine Monohydrate has a half-life of about 3 hours. Remember this. It is very important.

Mass Building Protocol
You want to get big. Whether you're a hard-gainer, or just a regular dude looking to pack on muscle, your dosing will be similar or the same depending on body weight. The best way for you to take Creatine Monohydrate would be the following.

Week 1 (Loading Phase)
5 Grams upon waking with Fruit Juice.
5 Grams four hours later, with Fruit Juice
5 Grams four hours later, with Fruit Juice
5 Grams four hours later, with Fruit Juice

That's 20 grams over 12 hours. At this rate, you will constantly have some Creatine in your bloodstream and it will be finding residence in your muscle tissue. Continue this protocol for about a week, and then do the following for maintenance:

Weeks 2 - 8 (Maintenance Phase)
2.5 Grams upon waking, with Fruit Juice
2.5 Grams four hours later, with Fruit Juice
2.5 Grams four hours later, with Fruit Juice
2.5 Grams four hours later, with Fruit Juice

It should be noted that while on Creatine Monohydrate, drinking A LOT of water is not only important, but required. Monohydrate has the ability to pull in extra water to your muscles, so supplying your body with A LOT of water is necessary for Creatine to maximize its muscle volumizing potential. Also, while you may not necessarily dehydrate while taking Creatine, the rest of your body still needs it's ample supply of H2O, so don't skimp on the water intake. 

During this cycle, you should see your body weight go up, as well as your strength. You may also notice you look "fatter" or more "puffy". Heavier guys, (like myself) tend to really look loaded n' bloated, whereas skinner people just look a little watery. This obviously varies from person to person. Overall, you should feel more stamina in the gym and more energy. When supplemented this way, you should get a real solid boost from the Creatine that you should most certainly feel. You will feel stronger than you normally do and move more weight as well.

Also of note is the fact that this was an eight week program. Creatine isn't required to be cycled, but I find that eight weeks of anything is good enough to see results from, and not too long where your body gets too comfortable with it. It's always good to throw your body for a loop. Feel free to experiment on that aspect.

When you finally come off of this regimen, you will immediately notice a few things. 
  • You will probably start urinating more due to excess fluids being removed. 
  • You will probably lose quite a few pounds (mostly water weight)
  • You may feel weaker or notice a decline in strength.
The last part is to be expected. As I explained in Part 1, your ATP production will be vastly slowed down. Overall, your numbers should be quite a bit higher than when you started your cycle.

If you are a heavier lad and are worried that you gained too much water weight and look too fat, you can do a couple of things to encourage the excess water to leave.

  1. Take an herbal diuretic for a week or two and drink a TON of water. (You will be pissing all over the place)
  2. Stop eating carbohydrates for 7-10 days.

Both of these will encourage excess water to leave your body.



Pre-Workout Boost
If you just want some "no-strings attached" energy production for the gym, but are a little worried about water retention, the following would be something to consider.

About 1 to 2 hours before the gym, have about 5 grams with some Gatorade or Fruit Juice. By the time you get to your lift, your serum levels will be peaking and you will get a slight boost in stamina and strength. Retaining water-weight is very unlikely, as a 5 gram dose will be fully utilized and eliminated during your training session. If you are worried about bloating just stop taking it for a couple of days. It will be flushed out by then.



Post-Workout Recovery
If you just want to take Creatine purely for it's recovery aspect of lowering myostatin levels, but are somewhat concerned about water retention, just throw some in your shake after training. 5 grams, with a simple carbohydrate such as Gatorade is sufficient. This would probably not be as effective as constantly taking Creatine throughout the day, as muscle repair is an on-going process that occurs long after a work-out is completed. Taking some earlier in the day to sustain levels longer could help too. It all depends on how concerned you are with water retention. Clearly, the "Mass Building Protocol" outlined above is the most effective way to keep Creatine in your bloodstream and in your muscles.


If looking "shredded" for beach season is your main concern, taking Creatine Monohydrate during the Summer probably wouldn't be the best idea. I personally don't think that 2.5 to 5 grams an hour before a work-out a few times a week will make someone look bloated per say, but we all know how the placebo effect is - as soon as that person feels a little more "puffy", the Creatine will get blamed. Meanwhile they probably had six beers Saturday night. 

That doesn't count though. Burgersfortheboys.


Other Types of Creatine

So what does that person looking for the six-pack during beach season take as far as Creatine? They don't want any water retention, because lets face it, if that six-pack becomes a four-pack, there's gonna be a problem. Non-loading, non-bloating formulas are pretty new to the scene in context to how long Creatine Monohydrate has been around. They have not been as vastly studied in comparison to Monohydrate as far as safety and effectiveness, so I can't really say I'm a huge fan. 


Creatine Hydrochloride
Creatine Hydrochloride is a Creatine salt, with the Hydrochloride (HCl) molecule greatly increasing absorption rate by the body. Currently, it is the most popular NON-MONOHYDRATE formula on the market. It's claim is that it is MUCH more soluble than regular Creatine, which makes it a "super-concentrated" dose. Personally, I've never tried it by itself. I've used a popular pre-workout drink which contained Creatine HCl it, so I can't really say in fairness just how effective it may or may not be. However, people who buy it seem to keep buying it which means it's doing something. 

Creatine HCl is ideal for people who don't want the bloating or the loading involved with regular Creatine Monohydrate. It may not yield the same results long term as far as muscle production and recovery, but as a pre-workout Creatine to give you a boost of energy, it's a good choice.


Kre-Alkalyn
Kre-Alkalyn is a form of Creatine that claims to be "pH buffered", created with the idea being that the harsh and acidic environment of your stomach won't cause the Creatine it contains to break down into the waste material known as Creatinine. The manufacturers of this product claim Creatinine is the cause of any and all side effects of Monohydrate supplementation. Kre-Alkalyn's manufacturers also claim that plain Creatine Monohydrate will start breaking down and producing Creatinine in an acidic environment within minutes. The problem with that claim however, is that Creatine Monohydrate supplementation only minimally effects Creatinine levels, as demonstrated by the following study. 


Even with long term supplementation of Monohydrate, it still has a limited effect on Creatinine levels. I personally don't buy the hoopla with Kre-Alkalyn, and I don't really recommend it. I've taken it before, and don't notice a difference.

It's usually taken pre and post-workout, and also claims "no loading" and "no bloating." These are essentially glorified Creatine Monohydrate pills.


Creatine Ethyl Ester
This really is not a good form of Creatine. An awesome study that I will link completely OWNS it.


Basically, the study done compared Monohydrate, a placebo, and CEE. Not only did Monohydrate outperform CEE, the placebo did in some areas as well. Monohydrate also yielded better results as far as absorption rates, and less Creatinine production, which ironically, the manufacturer claimed the opposite. This is a Creatine to stay away from.


Potential Side Effects

Really, there isn't anything to worry about with Creatine supplementation as far as serious side effects. Again though, with Monohydrate you need to consume more water to replenish what is absorbed into your muscles to avoid cramping. Gaining water weight and looking puffy is a side effect of Monohydrate supplementation as well. Creatine HCl is pretty safe so far, but it's relatively new and can't boast the same safety reputation as Monohydrate. Kre-Alkalyn is basically Monohydrate. I would definitely avoid Creatine Ethyl Ester though, because it is shown to raise serum Creatinine levels, which means less of the Creatine you ingest is actually being utilized, and more of it is being wasted.

Also of note, if you have kidney or renal disease, or your kidneys just aren't functioning correctly, (which if this is the case, taking Creatine to pack on some muscle should be the least of your worries) you should avoid Creatine. Creatine supplementation does put a very limited amount of stress on the kidneys, but no worries - those of us without kidney problems will have absolutely no issues taking Creatine as directed.


So if you couldn't tell already, I'm a little biased towards Creatine Monohydrate. Big whoop. I have an opinion. Like I said, and have stressed before, it's VERY IMPORTANT to find something that works with YOU. I can sing and dance all day about how Monohydrate is awesome, yields more energy, reduces myostatin levels, yadda yadda yadda, but you could buy Kre-Alkalyn tomorrow and swear it's the greatest shit since sliced bread. I just respond particularly well to Creatine Monohydrate, whereas some people do respond to it at all. 

In the history of dietary supplements, many have come, and many have gone. Stuff gets banned, reformulated, and discontinued countless times, only to come back five to ten years later with a new name and a new "partitioning technology." I can guarantee though, as long as there is a supplement industry and athletic competition, whether it be sports, bodybuilding, or fighting, plain old Creatine will still be around. As one of the most studied dietary supplements in history, it truly has, and always will, in my opinion, stand the test of time.

Matty D




Tuesday, May 1, 2012

Creatine, Part 1

May 1st 2012

Creatine.

It is probably the most thoroughly studied dietary supplement in America, and yet easily still one of the most misunderstood. There is not one other supplement I can think of that invokes more wives' tales, urban myths, and just flat out general bullshit than Creatine does. I never understood why there is so much nonsense revolving around it but alas, I will try and debunk any sort of myths and misgivings in this blog entry. This blog will be divided into two parts because it is indeed quite large and I feel that it will be more digestible and accessible that way.
Part one will cover the following: 
  • What is Creatine?
  • What does Creatine do?
  • Why you should take it
Part two will cover:
  • How to supplement Creatine
  • The different types of Creatine
  • The potential side effects of Creatine supplementation

Part 1

What is Creatine?

2-(carbamimidoyl-methyl-amino)acetic acid is the chemical name for it. I'm sure that doesn't mean shit to anyone reading this, but it's there for scientific reference in case you need it. You're welcome.

Before Creatine was ever a DIETARY SUPPLEMENT, it was a natural amino-acid compound found in vertebrate's skeletal muscle. (vertebrates, you know, those fuckers who have Spinal Cords?)

Something important to understand about Creatine, is that EVERYONE HAS IT IN THEIR BODY. Forget the supplement for a minute. Creatine is a substance found in all of our bodies. Everyone from Phil Heath (current Mr. Olympia), to the old cranky old dude across the street who never mows his lawn and leaves weird notes on your car, and even the fat soccer mom who thinks whey protein powders are synthetic anabolic steroids, all of them use Creatine each and everyday.

Luckily for us, our bodies are able to manufacture Creatine from just three simple amino acids, L-arginine , glycine, and L-methionine. That reaction, combined with the amount of Creatine contained in the foods that meat-eaters consume most, namely beef, yields more than enough Creatine for a human to ever need for regular everyday life - in 2012 that is. Humans 50,000 years ago had to hunt for food by killing and chasing down animals multiple times everyday. They had to move and act quickly. Sometimes they had to sprint, or jump, or climb, needing quick energy on demand. Creatine fuels this type of energy. This is where additional Creatine comes into play. Read on to find out what Creatine actually does.


What does Creatine do?

Creatine could simply but effectively be described in my opinion as an energy donator. It converts Adenosine Diphosphate (ADP) into the more readily available, high octane, ass-kicking molecule known as Adenosine Triphosphate (ATP). ATP is synthesized from the Citric Acid Cycle (or Krebs Cycle), which is responsible for relentlessly metabolizing energy in humans. ATP is unique in that it fuels your muscles for quick, short, and very powerful bursts of energy. The Krebs Cycle in tandem with Creatine metabolization will produce, on demand, the ATP necessary for whatever instant bursts you need it for. So, for that prehistoric caveman who needs to chase down Bambi or some fat wild hog, Creatine will help him enormously. Now normally, your muscles only have a few seconds worth of "quick-burst energy"aka ATP, but Creatine being the generous bastard that he is, will donate a Phosphate molecule to the still-cool-but-not-as-awesome ADP molecule to convert it to the readily available (you guessed it) ATP.



Why Should I take Creatine?

Okay. Let's talk about the benefits of supplementing Creatine in higher amounts than what one would attain from their normal diet. Really, the question here is, why WOULDN'T you? You've probably figured out by now why it could maybe be beneficial for someone on a strength training regimen to generate more quickly, and in higher frequency, instantaneous bursts of energy thereby minimizing recovery time, which could therefore enable you to LIFT MORE WEIGHT MORE OFTEN, RESULTING IN ACCELERATED STRENGTH AND MASS GAINS. If you haven't figured all of that out on your own by now, do the following:
  1. Take your hand.
  2. Clench your fist.
  3. Shove fist into head.
  4. Repeat.
I'm kidding don't do that. Oh you did it already? My bad. Keep going.

Yeah. So anyway. What about the rest of us in the gym who aren't out hunting wild hogs? (Except for me. Everyone who knows me, knows I'm out every Saturday night huntin' down wild hogs. SUUUWEEEET) If you've taken Creatine, you know that when you come off of a cycle, you "lose" some strength. Your bench might go down a little, your deadlift might go drop. You figure, "yeah that Creatine shit is good, but it just gives you fake muscles. It's just water." Yeah...no. Your numbers were "artificially" higher than what they should have been. Your bench increased by 20 lbs, where it would have normally only increased 5 or 10lbs. So before Creatine, your bench was at 135, you got it up to 155, now you're off of it and you can only get up 150. "WTF BRO I LOST STRENGTH THAT SHIT IS FAKE." Right. And you're retarded to boot. What a shame!

(For the record, I'm not using that word to in any way, shape, or form, make light of or insult anyone who is mentally challenged or handicapped, or anyone who knows of or is related to someone suffering from it. I for one admire and greatly respect the strength and will-power of all families who have a loved one suffering from such a condition. Support the struggles of the mentally handicapped and their families today by learning more and making a donation at http://www.aaidd.org/)

It is natural and almost expected for your numbers to drop a little bit. After all, your muscles were able to call upon more energy than usual, which gave them kind of an unfair advantage against gravity, wouldn't you say? So as cool as moving more weight is, there is another huge bonus to supplementing Creatine AFTER your training session as well. Creatine also has another function of lowering the "genetic speedbump" in our muscles known as Myostatin. Myostatin inhibits muscle growth. It's an anabolic police officer. Myostatin says to the muscles, 
"You guys can't get too big now. I don't want us to look like Barry Bonds, with that big head n' shit. Let's stay a normal size. I mean, what if we get chased by a Lion? We don't want you to weigh us down and make us lose some flexibility."

Myostatin protects humans (who aren't on any anabolic steroids or drugs) from getting too big and slow. In the event we are chased by that big fat wild hog (I can't get away from her, she really wants my shit), we need to be quick, flexible, and have average strength.

According to a study I will link here, (unfortunately you need to pay to view the FULL study, so the following is just the summary/conclusion), Creatine is the con-artist who pays off and bribes the cop (Myostatin) to turn the other cheek, if only temporarily.

Excerpt from the study:
The protocol consisted of 3 days per week of training for 8 weeks, each session including three sets of 8-10 repetitions at 60-70% of 1 RM for whole-body exercise. Blood sampling, muscular strength testing and body composition analysis (full body DEXA) were performed at 0, 4th and 8th weeks. Myostatin and GASP-1 was measured. Resistance training caused significant decrease in serum levels of myostatin and increase in that of GASP-1. Creatine supplementation in conjunction with resistance training lead to greater decreases in serum myostatin (p<0.05), but had not additional effect on GASP-1 (p>0.05). The effects of resistance training on serum levels of myostatin and GASP-1, may explain the increased muscle mass that is amplified by creatine supplementation.
Simply put, Creatine helps to inhibit Myostatin levels, which in turn equates to more muscle production.

Supplementing Creatine can result in more energy production during intense workouts, as well as more muscle production after your training by lowering Myostatin levels in the body. I really think it's a no-brainer for anyone who has ever picked up a weight to use a Creatine supplement. Your hard-work in the gym will be amplified by using it. As I said, why the hell WOULDN'T you take it?

Matty D 

Link to study
http://www.ncbi.nlm.nih.gov/pubmed/20026378